MAPT and supranuclear palsy, progressive, 1: Primary tauopathies, belonging to the heterogeneous group of FTDs comprising MAPT-associated FTD, AGD, CBD, CTE, PiD, and PSP, and characterized by behavior, language, and motor impairment, exhibit as their hallmark deposits of aggregated tau proteins in neurons and glial cells in the cerebral cortex and in other brain regions [11,21,22].