MAPT and supranuclear palsy, progressive, 1: Furthermore, in FTD and other tauopathies, such as CED, PD, and PSP, the MAPT gene presents two haplotypes: while the H1 haplotype can be detected in all ethnic groups, the H2 haplotype has been identified in European and southwest Asian populations and has been associated with a reduced risk of neurodegenerative diseases [6].