In the depression group, CBAS-BN had a direct effect on CES-D (estimate of the direct effect: 0.457, 95% BC CI: 0.132 to 0.767), whereas EROS significantly mediated the relationship between only CBAS-BN and CES-D (estimate of the indirect effect: 0.265, 95% BC CI: 0.120 to 0.451). This evidence concerns the gene CYBC1 and depressive symptom measurement.