All lncRNAs significantly correlated with at least one immune cell type in the TME, as determined by cell type deconvolution analysis (Fig. 7a). The risk score was found to be positively correlated with abundance of naïve T cells CD4 and negatively correlated with follicular helper T-cells and eosinophils in tumor microenvironment (Table 3). The differential expression of 19 immune checkpoint (IC) and ligand genes were also examined in high- and low-risk patients (Fig. 7b), and six IC genes were significantly differentially expressed (Fig. 7c). The gene discussed is CD4; the disease is neoplasm.