Of note, the ratio of CD163+/CD206+ TAMs to ovarian cancer cells was increased in omental metastatic tumors (p = 0.0234), and the ratio of CD86+ TAMs to ovarian cancer cells was not (p = 0.3777), indicating that the metastatic microenvironment skews CD163+/CD206+ TAM polarization (Fig. 1D; Supplementary Fig. S1B). Here, MRC1 is linked to metastatic neoplasm.