Moreover, we analyzed the Cancer Genome Atlas Ovarian Cancer (TCGA-OV) database, and found CD68+YAP1low groups exhibited dramatically increased M2-like TAMs markers expression, such as MMP9, CCL8, SPP1 and CCL17, when compared to CD68+ YAP1high (Supplementary Fig. S7D). This evidence concerns the gene SPP1 and ovarian carcinoma.