CRP and Increased total leukocyte count: At the age of 22 years, at 28 weeks of pregnancy, P1 was hospitalized for septic shock, presenting with leukocytosis (25.7 × 109 cells per litre) with neutrophilia (18.80 × 109 cells per litre), high C-reactive protein concentration (CRP; 8.7 mg dl−1) and persistent fever (>38 °C).