NFKB1 and chronic myelogenous leukemia, BCR-ABL1 positive: In leukemic cells, Yang and co-workers found that brassinin, a phytoalexin retrieved from cruciferous vegetables, induced autophagy by activating MAPK signaling pathway in K562 chronic myelogenous leukemia cells58, as Qin and colleagues who showed that hinokiflavone, a biflavonoid present in Selaginella tamarisina, induced autophagy in the same cells through MAPK/NF-κB signaling pathway59.