Interferon-gamma (IFN-γ) and interferon-alpha (IFN-α) response gene sets were significantly upregulated by rods, cones and Müller glia, as well as showing positive enrichment in other retinal cell types, suggesting signalling through these cytokines is one of the major mechanisms by which retinal cells respond to inflammatory conditions during autoimmune uveitis directed against IRBP. The gene discussed is RBP3; the disease is autoimmune uveitis.