A detailed cross-comparison with other myeloma models [33] showed pronounced parallels (Fig. 6b, Supplementary Fig. 4a), most notably with the model induced by KRASG12D in conjunction with BCL2 overexpression, which exhibited the highest similarity (p = 1.8 × 10−246; odds ratio (OR) = 3.7). The gene discussed is BCL2; the disease is plasma cell myeloma.