TOPORS and myelodysplastic syndrome: To validate the CRISPR-Cas9 screening results, sgRNAs against TOPORS, Cas9, and GFP were introduced into MOLM-13, MDS-L, SKK-1 (MDS/AML cell line), and SKM-1 (MDS/AML cell line) cells (Supplementary Data 1) via lentivirus.