Nutritional supplements based on Zinc, Prebiotics, Probiotics and Vitamins [22], amifostine [23] and the oral CXCR4 Inhibitor X4-136 were also reported to be useful in patients treated with pelvic RT not only for cervical and endometrial cancer but also for anal and rectal cancer [24]. Here, CXCR4 is linked to endometrial cancer.