Twelve of these are within the list of leading prioritized genes as potential drug targets reported by a recent study integrating asthma GWAS information with protein-protein interaction data (IL-6, MYC, PRKCQ, ETS1, IL-4R, IRF1, IL-1R2, RELA, CDK2, SOCS1, NFKB2, PSMA6).66 This evidence concerns the gene IRF1 and asthma.