VIM and neoplasm: Immunohistochemical staining of tumors for EpCam (epithelial marker) and vimentin (mesenchymal marker) showed that the fraction of epithelial, EpCam-positive, cells was more than 90% in tumor xenografts (Figure 2—figure supplement 1) and on average 76 ± 10% in patients’ tumors (Figure 3—figure supplement 1).