F8 and hemophilia A: These values are very close to the upper limit of the reimbursement guidelines for patients with severe hemophilia A in Korea (up to 30 IU/kg, 3 times/week for standard half-life FVIII concentrates, such as octocog alfa, and 30 IU/kg, 2 times/week for extended half-life FVIII concentrates, such as rurioctocog alfa pegol) [7].