Ronellenfitsch et al. reported activating ERBB2 mutations (p.Leu755Ser, p.Asp769Tyr, p.Val777Leu) in 3 of 7 (43%) patients with schwannomatosis, but in none of 8 NF2-asscoiated or sporadic hybrid schwannoma-neurofibroma cases [27]. The gene discussed is ERBB2; the disease is plexiform neurofibroma.