The alleviation of cardiac arrhythmias was also supported by Nav1.5 protein relocalization to cell–cell junctions in PKP2 Hom hearts; however, future studies focused on evaluating the biophysical properties of the sodium channel will be required to fully determine its importance in the rescue of the electrophysiological abnormalities associated with PKP2-related disease. The gene discussed is PKP2; the disease is cardiac arrhythmia.