A study by Moro and co-authors [21] showed that following bilateral subthalamic nucleus (STN) DBS surgery, in 11 PRKN mutation carriers (6 biallelic and 5 monoallelic), both mutation carriers and non-carriers exhibited an approximately 42% improvement in motor scales including Unified Parkinson’s Disease Rating Scale part III (UPDRSIII) 3–6 years post treatment. Here, PRKN is linked to Parkinson disease.