Aside from the altered PC/LPC profiles in our cohort, obesity was associated with several-fold increases in saturated ceramide species such as Cer d18:0, Cer d19:0, Cer d37:0, Cer d39:0, Cer d40:0, Cer d42:0, and several others. This evidence concerns the gene CBLN1 and obesity due to melanocortin 4 receptor deficiency.