LAP3 and type 2 diabetes mellitus: Figure 4A shows the top five items for BPs, CCs, and MFs. The highly enriched GO items in the BPs were the signaling receptor ligand precursor processing, response to peptide, response to hormone, and others. In terms of CCs, the highly enriched GO items were the external side of the plasma membrane, the side of the membrane and an early endosome. In the MFs, the highly enriched GO items were the peptidase activity, endopeptidase activity, and peptide binding. These processes are intimately linked with the pathogenesis and complications of T2D [34,35,36].