BRCA1 and neoplasm: In agreement with national [45,46] as well as international guidelines [16,17,18,19,20,21,22], the paper states that the eligibility for BRCA1/2 mutation testing is based on personal and family history, taking into account the number of affected relatives, the type of neoplasms, the presence of multiple primary tumours, the age at diagnosis, the sex, and the immunohistochemical and molecular characteristics of tumours.