Measuring concentrations of tumor markers for HCC, namely alpha-fetoprotein (AFP) and des-gamma-carboxyprotein (DCP), is less invasive and more common than tumor biopsy or imaging, and is widely used not only for diagnosing HCC, but also as an adjunctive diagnosis to determine treatment efficacy for HCC [4,5]. This evidence concerns the gene ACE and hepatocellular carcinoma.