Following infection of the OE with SARS-CoV-2, damage or loss of cilia, along with down-regulation of the expression of the ciliary olfactory receptor and key olfactory signaling factors cyclic nucleotide gated channel subunit alpha 2 (CNGA2) and ADCY3, were observed in mice, resulting in abnormal olfaction in mice [114]. Here, CNGA2 is linked to infection.