CD4 and cytomegalovirus infection: In conclusion, our study showed that if we considered the percentage of HCMV-specific CD4+ T cells, the CFC-iCL and pp65 pool assays were the best predictors of self-resolving HCMV infection, while, if we considered the absolute number of HCMV-specific CD4+ T cells, the CFC-pp65 pool was the best predictor of self-resolving HCMV infection.