In contrast, when we considered the absolute number, the CD4+ CFC-pp65 pool assay was the best predictor of self-resolving HCMV infections and showed the best AUC (0.81; 95% CI: 0.66 to 0.95), while the AUCs for the CD4+ CFC-iDC, CFC-iCL, ELISPOT-iCL and ELISPOT-pp65 pool were slightly inferior (0.72 to 0.76). This evidence concerns the gene CD4 and cytomegalovirus infection.