GOT1 and neoplasm: cAspAT was identified as a less-abundant protein in the deep tumor region, and this result can be rationalized by considering that in CRC cells of the internal tumor part, the defective transamination of cytosolic aspartate in oxalacetate may favor the use of aspartate in the synthesis of asparagine, proteins, and nucleotides promoting the cell growth (Figure 6b).