Their observation that mean IGF1 levels were lowest in infants developing stage 3 ROP (17.0 ng/mL) compared to those with no ROP (20.0 ng/mL) during PMA weeks 28–33, even after adjusting for birth weight and gestational age, resonates with our findings of significantly lower IGF1 levels being predictive of ROP development. The gene discussed is IGF1; the disease is retinopathy of prematurity.