Syndromes associated with acromegaly include multiple endocrine neoplasia type 1 (MEN1) and type 4 (MEN4), Carney complex type 1 (CNC), McCune–Albright syndrome (MAS), the 3P association (3Pa), and neurofibromatosis type 1 (NF1). This evidence concerns the gene CDKN1B and acromegaly.