HMGB1 and infarction: Andrassy et al. demonstrated, via magnetic resonance imaging, that HMGB1 expression is associated with infarction size for STEMI area under curve (AUC) = 0.93, (95% CI = 0.85–0.98) and NSTEMI AUC = 0.96 (95% CI = 0.86–0.99) [119].