While no significant differences emerged for IL-6, IL-1α, IFN-γ, MCP1, and IL-12p70, the levels of IL-1β, IL-8, IL-10, IL-27, IP-10, and TNF-α appeared deregulated in serum from patients with COVID-19 compared to healthy donors (HD) (Figure 1). This evidence concerns the gene IL1B and COVID-19.