Considering that DISC1 is associated with the development of mental illnesses and the impairment of interpersonal relationships, we investigated if social interaction phenotypes are affected in transgenic flies carrying an insertion of hflDISC1, either on the second chromosome (UAS-hflDISC1-2nd) or the third (UAS-hflDISC1-3rd). The gene discussed is DISC1; the disease is psychiatric disorder.