Thus, the aim of our study was to quantify circulating miRNAs (miRNA126, miRNA146, and miRNA21), as well as the levels of MMP-1 and MMP-9, and to determine their association with left ventricular (LV) function and with arterial function, in patients with either ST-segment elevation acute myocardial infarction (STEMI) and stable ischemic heart disease (SIHD). This evidence concerns the gene MMP9 and coronary artery disorder.