CTLA4 and cancer: While some work groups have found an association between some CTLA-4 variants and cancer, like the single nucleotide polymorphisms (SNP) +49 A/G in exon 1, −1661 A/G, −318 C/T, and −17,722 T/C in the promoter region, or CT60A/G in the 3′-UTR [38], we are showing for the very first time the association between the VNTR (AT)n in NMSC.