To assess the impact of Ulmus macrocarpa extract and catechin 7-O-β-D apiofuranoside on muscle degradation and synthesis in a dexamethasone-induced muscle atrophy model, this study investigated the protein and gene expression of key biomarkers: myoD, myogenin, atrogin-1, and MuRF1. This evidence concerns the gene TRIM63 and muscle atrophy.