The findings show that there was no statistically significant association between the risk of preeclampsia and fetal REN polymorphisms (rs5705, rs5707, and rs2368564) (additive model: OR 0.94, 95% CI 0.80 to 1.10, I2 = 69.1%, n = 3; dominant model: OR 0.61, 95% CI 0.43 to 0.88, I2 = 89.2%, n = 3; recessive model: OR 1.03, 95% CI 0.90 to 1.17, I2 = 0.0%, n = 3). Here, REN is linked to preeclampsia.