In the liver of T2DM mice treated with this extract, a reduction was observed in ROS, IKKβ/NF-κB p65, and JAK2/Stat3/5B signaling pathways, leading to a decrease in the expression levels of iNOS, suppressor of cytokine signaling 3 (SOCS3), and inflammatory mediators. The gene discussed is SOCS3; the disease is type 2 diabetes mellitus.