Recently, it has been reported that chemoresistance is due, at least in part, to the high expression, in glioblastoma stem cells (GSCs), of members, such as ABCB4, of the ATP-binding cassette (ABC) transporters; moreover, ABCB4 can be transferred to the neighboring cells via EVs [190]. The gene discussed is ABCB4; the disease is glioblastoma.