Several blood-based protein biomarker candidates for endometrial cancer detection were suggested, including the Apolipoprotein family (APOA1/4, APOC1/2/3, and APOE), Clusterin (CLU), Inter-alpha-trypsin inhibitor heavy chain (ITIH2 and ITIH4), and Antithrombin III (ATR/SERPINC1). The gene discussed is ITIH2; the disease is endometrial cancer.