To effectively differentiate between endometrial cancer and normal endometrium, a 4-biomarker panel with CSTA, S100A7, MMP9 and SERPINA10 and a 10-biomarker panel adding RTN4, LAMP2, WDR1, KRT13, ALDH2 and ILF were created showing elevated specificity. Here, MMP9 is linked to endometrial cancer.