ROC analysis identified ten proteins with high performance as diagnostic biomarkers for endometrial cancer: MPO, CADH1, SPIT1, ENOA, MMP9, LDHA, CASP3, PKM, PRDX1, and OSTP isoform A. Among these, MPO, CADH1, SPIT1, and OSTP isoform A exhibited the greatest performance [51]. This evidence concerns the gene PKM and endometrial cancer.