In that work, the assertion of “pathogenic” was based on a multifactorial likelihood analysis performed according to the method first described by Goldgar et al,17 incorporating information on bioinformatic prediction for the amino acid position, co‐segregation in four families, lack of co‐occurrence with another BRCA1 pathogenic variant in 3827 probands, histopathology of five breast cancer (BC) and nine OC carriers, and tumor loss of heterozygosity (LOH) in four BC and six OC cases. The gene discussed is BRCA1; the disease is neoplasm.