29 Kittleson Kittleson M M Hurwitz Hurwitz S S Shah Shah MR MR Nohria Nohria A A Lewis Lewis E E Givertz Givertz M M et al et al Development of Circulatory-renal Limitations to Angiotensin-converting Enzyme Inhibitors Identifies Patients with Severe Heart Failure and Early Mortality Development of Circulatory-renal Limitations to Angiotensin-converting Enzyme Inhibitors Identifies Patients with Severe Heart Failure and Early Mortality J Am Coll Cardiol J Am Coll Cardiol 2003 2003 41 41 11 11 2029 2029 2035 2035 10.1016/s0735-1097(03)00417-0 10.1016/s0735-1097(03)00417-0 12798577 12798577. Here, ACE is linked to heart failure.