Serum acid phosphatase (ACP) is mainly derived from the liver, erythrocytes and platelets In hepatitis, cirrhosis, abnormal liver metabolism, and extrahepatic and intrahepatic obstructive biliary diseases and cirrhosis (Peng et al., 2015), the enzyme levels of AKP and ACP are greatly increased (Shang et al., 2003). The gene discussed is NDUFAB1; the disease is hepatitis A virus infection.