In terms of cytokine production, both CD49a+ and CD49a-CD103+CD8+ TRM cells produced high levels of IFN-γ but not IL-17A in vitiligo patients, whereas CD49a+ and CD49a-CD103+CD8+ TRM cells produced high levels of IFN-γ and IL-17A, respectively, in patients with psoriasis [199, 201]. The gene discussed is ITGAE; the disease is vitiligo.