Due to the absence of substantial disparities in the protein levels of CAB39L, ETV7, OVOL2, and ZHX2 between neoplastic and neighboring tissues (Supplementary Figure S4C) and the lack of known immunohistochemical results for ARRDC3 in CRC, ChIP-PCR analyses were employed for ANXA7 and CLDN7 (Figure 6E). This evidence concerns the gene ARRDC3 and colorectal carcinoma.