The yellow cluster consisted of 21 keywords, including AKT, AMPK, biguanide, cancer metabolism, cancer stem cells, chemoresistance, chemotherapy, cisplatin, colon cancer, glioblastoma, glycolysis, hypoxia, LC, metabolism, metformin, mitochondria, ovarian cancer, oxidative stress, p53, and phenformin. This evidence concerns the gene AKT1 and cancer.