IFNG and gastritis: In a murine model of AIG, increased levels of IFNγ+ CD4+ T cells have been observed (Suri-Payer and Cantor, 2001), a finding validated in the TxA23 mouse model, where IFNγ is directly involved in the death of gastric epithelial cells, leading to the development of chronic atrophic gastritis (Tu et al., 2012).