ERBB2 and papillary adenocarcinoma: This study highlights the association of HER-2 status in gastric and gastroesophageal junction carcinomas with specific clinicopathological features. Our findings indicate that HER-2 positivity is notably higher in patients at the extremes of age, as well as those with tubular adenocarcinoma and papillary adenocarcinoma, and moderately to poorly differentiated tumors.