ERCC1 and cancer: For example, in ACC, KIRC, LAML, and LUAD, higher ERCC1 expression was correlated with poorer overall survival (OS), suggesting that ERCC1 plays a tumor-promoting role in these cancers, whereas in BRCA and GBM, the expression level of ERCC1 was positively correlated with the patients’ overall survival (OS), indicating that ERCC1 plays a role in inhibiting tumor development.