Notable among genes that shared expression patterns among eosinophilic disorders compared to controls was the upregulation of MTRNR2L1 in four level one cell types (B, CD4+ T, CD8+ T, and DC) and upregulation of several cell cycle associated genes in CD4+ T cells (Table 1; Figure 3; Supplementary File 1 Table D). Here, CD4 is linked to eosinophil disorder.