By directly combining the 3’ Untranslated Regions (UTR) with ACSL4, mir-424-5p inhibits the expression of ACSL4, thereby reducing the ferroptosis induced by erastin and RSL3, thereby lowering the sensitivity of ovarian cancer tissue to ferroptosis, ultimately leading to the malignant progression of OC (71). The gene discussed is ACSL4; the disease is ovarian carcinoma.