Several staging protocols and scoring systems such as the Barcelona Liver Cancer Staging system, China Liver Cancer Staging Programme, Tumor Node Metastasis staging system, and bilirubin, albumin (ALB), Lens culinaris agglutinin A–reactive fraction of alpha-fetoprotein (AFP), and des-γ-carboxy prothrombin score are in use [6]. This evidence concerns the gene AFP and liver cancer.