METTL3-mediated m6A modification enhances the stability of KRT7-AS/KRT7 mRNA through the IGF2BP1/HuR complex, whereas FTO regulates the translation elongation of KRT7 mRNA via YTHDF1/eEF-1.Knockdown of METTL3 or overexpression of FTO can inhibit the intra- and extra-tumoral metastasis of breast cancer cells [67]. This evidence concerns the gene FTO and breast carcinoma.