Silencing lncRNA URB1-AS1 increases the sensitivity of HCC cells to sorafenib in vivo [186].Together, these results suggest that lncRNA URB1-AS1 promotes sorafenib resistance by inhibiting ferroptosis, highlighting that targeting the lncRNA URB1-AS1 is a potential regimen to overcome resistance to sorafenib in HCC [186]. Here, URB1 is linked to hepatocellular carcinoma.