Previous work from our group on the differential regenerative potential of source-specific MSCs have shown that the secretome from UC-MSCs is enriched in the expression of anti-inflammatory molecules (i.e., IL4, IL13, IL12, IL35), compared to adult sources of MSCs (AD-MSCs and BM-MSCs) [17, 41]; these molecules can also effectively rescue cells from apoptosis and promote immune cell polarization to an anti-inflammatory phenotype. The gene discussed is IL13; the disease is Alzheimer disease.